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Upstream Bio, Inc.
Nasdaq · CIK 2022626
Last close5.04
Daily change+0.00 (0.00%)
10 Years gain-77.09%
Dividends TTM0
Dividend yield0.00%
Fundamental Analysis
UPB · STANDARD
SIC 2834 · Pharmaceutical Preparations · Fiscal year end 1231
Fundamental
55.3Momentum
0.0Acceleration
0.0Confidence
63.0Annual Revenue3
Quarterly Revenue9
Annual CFO3
Balance SheetAvailable
RankingEligible
Score Breakdown
Growth25.0 / 25
Quality12.5 / 25
Capital Efficiency0.0 / 20
Balance Sheet15.0 / 15
Shareholder Economics0.0 / 10
Forward Indicators0.0 / 5
Signals
No positive signals calculated.
Warnings
Operating margin compression · MEDIUMOperating margin compressed by 1314.3075 percentage points.
Key Metrics
Revenue Growth TTM47.52%OK
Revenue CAGR 3Yn/aINSUFFICIENT_HISTORY
Gross Margin100%OK
Operating Margin-4,907.03%OK
FCF Marginn/aMISSING
FCF Growthn/aINSUFFICIENT_HISTORY
ROIC-279.12%OK
Incremental Operating Margin 3Yn/aNOT_MEANINGFUL
Net Debt / CFOn/aNOT_MEANINGFUL
Diluted Share Growth 1Y1.77%OK
SBC / Revenuen/aMISSING
SBC / FCFn/aNOT_MEANINGFUL
Financial History
| Period | Revenue | Gross Profit | Operating Income | CFO | FCF | Gross Margin | Op Margin | FCF Margin | ROIC | Shares |
|---|---|---|---|---|---|---|---|---|---|---|
| 2025 FY Dec 31, 2025 | $2.85M | $2.85M | -$160.36M | -$133.28M | -$133.44M | 100% | -5,618.82% | -4,675.54% | n/a | 53.85M |
| 2025 FY Dec 31, 2024 | $2.37M | $2.37M | -$77.76M | -$59.17M | -$59.68M | 100% | -3,281.18% | -2,518.27% | n/a | 13.68M |
| 2024 FY Dec 31, 2023 | $2.38M | $2.38M | -$40.11M | -$37.93M | -$38.07M | 100% | -1,685.46% | -1,599.58% | n/a | 2.95M |
Formula Trace
| Metric | Value | Formula | Status | Source |
|---|---|---|---|---|
| Revenue TTM | $3.43M | sum latest 4 fiscal quarters Revenue | OK | 0001193125-26-343417, 0001193125-25-265713 |
| Revenue Growth TTM | 47.52% | Revenue_TTM / Revenue_TTM_1Y_ago - 1 | OK | 0001193125-26-343417, 0001193125-25-265713 |
| Revenue CAGR 3Y | n/a | (Revenue_current / Revenue_3Y_ago)^(1/3) - 1 | INSUFFICIENT_HISTORY | 0001193125-26-126188 |
| Revenue CAGR 5Y | n/a | (Revenue_current / Revenue_5Y_ago)^(1/5) - 1 | INSUFFICIENT_HISTORY | 0001193125-26-126188 |
| Gross Profit CAGR 3Y | n/a | (GrossProfit_current / GrossProfit_3Y_ago)^(1/3) - 1 | INSUFFICIENT_HISTORY | 0001193125-26-126188 |
| Operating Income Growth | n/a | OperatingIncome_current / OperatingIncome_prior_year - 1 | INSUFFICIENT_HISTORY | 0001193125-26-343417, 0001193125-25-265713 |
| FCF Growth | n/a | FCF_current / FCF_prior_year - 1 | INSUFFICIENT_HISTORY | derived |
| Revenue Growth Acceleration | n/a | 0.5*(Q0-Q1)+0.3*(Q1-Q2)+0.2*(Q2-Q3) | INSUFFICIENT_HISTORY | derived |
| Gross Profit Acceleration | n/a | 0.5*(Q0-Q1)+0.3*(Q1-Q2)+0.2*(Q2-Q3) | INSUFFICIENT_HISTORY | derived |
| Operating Income Acceleration | n/a | 0.5*(Q0-Q1)+0.3*(Q1-Q2)+0.2*(Q2-Q3) | INSUFFICIENT_HISTORY | derived |
| FCF Acceleration | n/a | 0.5*(Q0-Q1)+0.3*(Q1-Q2)+0.2*(Q2-Q3) | INSUFFICIENT_HISTORY | derived |
| Gross Margin | 100% | Gross Profit / Revenue | OK | 0001193125-26-343417, 0001193125-25-265713 |
| Operating Margin | -4,907.03% | Operating Income / Revenue | OK | 0001193125-26-343417, 0001193125-25-265713 |
| ROIC | -279.12% | NOPAT / Average Invested Capital | OK | 0001193125-26-343417, 0001193125-25-265713 |
| Net Debt / CFO | n/a | Net Debt / CFO | NOT_MEANINGFUL | 0001193125-26-343417 |
| Current Ratio | 27.99x | Current Assets / Current Liabilities | OK | derived |
| Revenue per Diluted Share | $0.06 | Revenue / Diluted Shares | OK | 0001193125-26-343417, 0001193125-25-265713 |
| SBC / FCF | n/a | SBC / FCF | NOT_MEANINGFUL | derived |